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AI Overview

The book "Microtubules" by Pierre Dustin is a comprehensive monograph on the structure, function, and biology of microtubules. Here is a detailed overview of the book:

Key Themes

  1. Historical Background: The book begins with a historical overview of microtubules, tracing their discovery and early research developments.
  2. Structure and Chemistry: It delves into the general morphology and structure of microtubules, as well as their biochemistry and associated proteins.
  3. Assembly and Disassembly: The book discusses the assembly and disassembly processes of microtubules in vitro, highlighting the regulatory mechanisms involved.
  4. General Physiology: It explores the synthesis and regulation of tubulin, the protein that makes up microtubules, and their assembly in vivo. It also examines their interactions with other cell structures and organelles.
  5. Complex Microtubule Assemblies: The book covers complex microtubule assemblies such as axonemes, centrioles, basal bodies, cilia, and flagella, providing detailed descriptions of their structures and functions.

Plot Summary

The book is structured into several chapters that provide a systematic approach to understanding microtubules:

  1. Introduction and Historical Background: Sets the stage for the study of microtubules by providing a historical context.
  2. Structure and Chemistry of Microtubules: Explores the morphological and biochemical aspects of microtubules.
  3. General Physiology of Tubulins and Microtubules: Discusses the synthesis, regulation, and assembly of tubulin in cells.
  4. Complex Microtubule Assemblies: Examines specific types of microtubule-based structures found in cells, such as axonemes and centrioles.

Critical Reception

While specific reviews are not readily available, the book's comprehensive nature and detailed coverage of microtubules suggest it has been well-received by the scientific community. The fact that it has been reprinted multiple times indicates its enduring relevance and utility in the field of cell biology.

Editions and Publication Details

  • Publication Date: The book was originally published in 1978, with a second edition released in 1984. The softcover reprint of the second edition was published in 2011 by Springer Berlin Heidelberg.
  • ISBN-13: 9783642696541.
  • Pages: 484 pages.

Overall, "Microtubules" by Pierre Dustin is a seminal work in the field of cell biology, offering a thorough examination of microtubules and their roles in cellular processes. Its detailed structure and comprehensive coverage make it a valuable resource for researchers and students in the field.