Stockley's Drug Interactions
A Source Book of Interactions, Their Mechanisms, Clinical Importance and Management
By: Karen Baxter
First published over twenty years ago, Stockley's Drug Interactions is still the most indispensable and authoritative international source of drug interaction information. Based upon the many thousands of published clinical papers and reports, it provides a series of detailed yet concise monographs designed for quick and easy reference. Each monograph contains a summary, clinical evidence for the interaction under discussion, its probable mechanism, clinical importance and management. Individual interactions are assembled alphabetically into chapters, grouped therapeutically, pharmacologically or individually. Both Recommended International Nonproprietary Names (rlNN) and US Adopted Names (USAN) are used throughout the book
AI Overview
"Stockley's Drug Interactions," edited by Karen Baxter, is a comprehensive reference book that has been a leading authority on drug interactions for several decades. Here is a detailed overview of the book:
Key Themes
Comprehensive Coverage: The book covers interactions between various types of medications, including therapeutic drugs, proprietary medicines, herbal medicines, foodstuffs, drinks, pesticides, and drugs of abuse.
Clinical Evidence: It provides detailed, evidence-based monographs that include an assessment of the clinical importance of each interaction and clear guidance on how to manage the interaction in practice.
New Additions: The latest edition includes over 3,400 monographs, with more than 300 new additions. It also features three new chapters on thyroid hormones, urological drugs, and nutritional agents, supplements, and vitamins.
New Drugs and Updates: The book includes information on new drugs launched in the last two years, such as fesoterodine, monoclonal antibodies, new antidiabetics (e.g., sitagliptin), new antineoplastics (e.g., dasatinib), and new immunosuppressants (e.g., temsirolimus).
Mechanisms and Genetic Factors: It provides increased commentary on the involvement of newer mechanisms in drug interactions, such as drug transporter proteins and other genetic factors that affect the ability of individuals to metabolize medicines.
Critical Reception
Authority and Practicality: The book is described as a very practical resource due to its concise yet detailed monographs, making it a valuable tool for healthcare professionals.
Comprehensive and Authoritative: It is recognized as the world's most comprehensive and authoritative reference book on drug interactions, providing a reliable source for healthcare professionals to manage drug interactions effectively.
Clinical Relevance: The eighth edition, for example, includes more than 3,100 detailed monographs, which are clinically relevant and evidence-based, making it a trusted resource in the medical field.
Plot Summary
The book does not have a narrative plot but rather a structured compilation of monographs detailing various drug interactions. Each monograph includes information on the mechanism of interaction, clinical importance, and management strategies. The content is organized in a way that allows healthcare professionals to quickly assess potential drug interactions and provide appropriate guidance.
In summary, "Stockley's Drug Interactions" by Karen Baxter is a seminal reference book that has been a cornerstone in the field of pharmacology and clinical practice. Its comprehensive coverage, detailed monographs, and continuous updates make it an indispensable resource for healthcare professionals managing drug interactions.